INS and Hyperglycemia: As the alloxan treated mice were incapable of synthesizing insulin in the system9, it was concluded that the increase of the plasma insulin concentration was due to the feeding of the milk insulin preparation from which the hypoglycemic hormone in digestive tract in these animals was able to enter into the circulation to produce the insulin effect in the control of hyperglycemia to normoglycemic level in the type I diabetic mice model.