TNKS and infection: In our study, the tankyrase inhibitors Endo-IWR-1 and JW67 inhibited RVFV MP12-GFP infection by greater than 50% in RVFV disease-relevant primary human hepatocytes (Fig. 4D), and JW67 significantly reduced infection of cells with wild-type RVFV, LCV, and CEV.