MEF2B and mantle cell lymphoma: Recently, two whole-genome and/or whole-exome sequencing (WES) studies on 29 and 56 MCL cases, respectively, identified additional mutated genes, including those encoding chromatin modifiers (WHSC1, MLL2, MLL3, MEF2B and SMARCA4), a cell adhesion factor (FAT4), cell cycle regulators (SMC1A and POT1), an anti-apoptotic factor (BIRC3) and NOTCH2 [22, 23].