Although mutations in SDCCAG8 were demonstrated to cause a retinal-renal ciliopathy in association with Senior-Loken syndrome and BBS-like features, the function of SDCCAG8 within the cilium and its associated structures n of SDCCAG8 within the cilium and its associated structures–centriolar satellites and basal body is poorly understood [1]. The gene discussed is SDCCAG8; the disease is Senior-Loken syndrome.