IFNA1 and dengue disease: Maximum plasma levels of IFN-α were generally not seen and took placebefore to peak viraemia in DENV-3 infected children (Libraty et al. 2002), and more recently in an elegant study, Gandini et al. 2013 demonstrated that circulatingplasma levels of IFN-α were higher in mild dengue compared with severe dengue or healthycontrols (Gandini et al. 2013).