However, at this time it could not be excluded that simply the metastatic latency was increased in the serglycin-deficient F2 mice (75% C57BL/6 and 25% FVB/n) as tumour onset is delayed at PyMT expression in congenic C57BL/6 mice compared to congenic FVB/n mice[42]. Here, SRGN is linked to neoplasm.