The Affymetrix microarray analysis also showed that the CCL2 mRNA expression level was increased in the SG-/- primary tumours (Fig 5 and Table 1), but no difference was found at the protein level (Fig 3 and S3 and S4 Figs) suggesting a serglycin-dependent effect on the CCL2 levels. Here, SRGN is linked to neoplasm.