LGALS1 and neoplasm: In this study we establish the overexpression of galectin-1 in the TNBC stroma using the murine tumor model system with an appropriate representation of the tumor microenvironment developed in our laboratory we have investigated the therapeutic efficacy as well as the biocompatibility of the radiation enhanced galectin-1 targeting with anginex conjugated arsenic trioxide (ATO) and cisplatin loaded liposomes to the TNBC microenvironment.