FASN and neoplasm: To confirm that loss of FASN-driven exacerbated FA biogenesis irreversibly re-orientates tumor cells to a stable and permanent commitment to differentiation, we excised tumor tissues from CA1d and CA1D/FASN shRNA#28-injected animals (Figure 2) and serially transplanted them into mammary fat pats of athymic nude mice (Figure 4A).