EPHA5 and colorectal carcinoma: In the present work, we find that NOVA2 uniquely regulates a series of alternative splicing events of axon guidance related genes, including deleted in colorectal carcinoma (Dcc), Roundabout, Axon Guidance Receptor, Homolog 2 (Robo2), Slit homolog 2 (Slit2), and EPH Receptor A5 (Epha5).