RNF180 and neoplasm: The mean tumor sizes in nude mice transfected with the four kinds of MGC-803 cell lines with various CpG island demethylation in RNF180 DNA promoter were significantly smaller than those transfected with MGC-803-vehicle cells at a four-week time-point after cell implantation (PCpG-116 VS vehicle =0.031, PCpG-80 VS vehicle =0.014, PCpG+97 VS vehicle =0.001, and PCpG+102 VS vehicle <0.001).