Not only DCs but also lymphocytes, in particular CD8+ T-cells, were observed in significantly higher numbers inside the DC-carrying matrices harvested from tumor bearing mice (9.1% + 0.8%) than that harvested from normal mice (4.3% + 0.3%) (Figure 4C), indicating that the tumor-exposed lymphocytes had higher propensity to move towards the signals originated from DCs-in-scaffold. The gene discussed is CD8A; the disease is neoplasm.