No significant difference for tumour cell apoptosis was observed between Tspan5-overexpressing cells and control cells in either AGS (4.61±1.22 versus 5.04±0.59, P=0.521) or MKN45 (8.87±0.71 versus 9.03±0.89, P=0.812) (Supplementary Figure). The gene discussed is TSPAN5; the disease is neoplasm.