SULF2 and cancer: The normalized SULF2 values for HNSCC patients (n = 8) were compared to cancer free controls (n = 8) and tended towards (p-value = 0.041) a higher ratio (mean = 7.41 × 10−6, SD = 8.59 × 10−6) compared to control samples (1.20 × 10−6, SD = 1.09 × 10−6) (Figure 5B), with some HNSCC patients having up to 10 x more SULF2 than the control mean.