SMARCB1 and neoplasm: Treatment with EPZ-6438 caused also apoptosis in cell lines and dose-dependent tumor regression in xenograft model of malignant rhabdoid tumors with mutated SMARCB1 (also known as SNF5, INI1, and BAF47), a subunit of the SWItch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complex [124].