Regarding other LSD1 inhibitors, ORY-1001 from Oryzon is in phase I/IIA trial for the treatment of acute leukemia, GSK2879552 is under a phase I clinical trial in patients with AML and SCLC, and 4SC-202, a HDAC1-3 and LSD1 inhibitor ended a phase I trial for hematological malignancies. This evidence concerns the gene HDAC1 and acute leukemia.