SERPINB5 and hepatocellular carcinoma: Haplotype block2 spanning the region of 17 kb coding region of SERPINB5 containing the HCC-risk-associated nonsynonymous SNPs (nsSNP) have been found in at least 60 residues (http://www.ncbi.nlm.nih.gov/SNP/ snp_ref.cgi?locusId = 5268), including rs2289519, rs2289520 and rs1455555 (Table S1), although single SNP has not significantly increase susceptibility associated with HCC.