The results demonstrate that low SOD2 protein expression is indeed an independent predictor for poor OS (HR = 2.310, 95% CI = 1.031-5.178, p = 0.042) and RFS (HR = 1.809, 95% CI = 1.037-3.156, p = 0.037) in patients with HCC (Table 2), suggesting that SOD2 protein is a useful prognostic biomarker for HCC patients. This evidence concerns the gene SOD2 and hepatocellular carcinoma.