Since the EMT phenotype—a hallmark of the mesenchymal colon cancer subtype—can be induced by TGFβ, and the TGFβ signaling pathway is predicted to be active based on gene expression in CMS4 CRCs (Guinney et al, 2015) and SSAs (De Sousa E Melo et al, 2013), we wondered whether TGFβ might also dictate subtype‐specific gene expression. This evidence concerns the gene TGFB1 and colonic neoplasm.