SACK1D and cancer: Moreover, other interactions are noted in the Biogrid interaction repository between FAM83 proteins and key cancer-associated proteins such as BRCA1 (FAM83A), CK1α, ß, and δ (FAM83D, G, and H), GADD45 (FAM83D), GSK3ß (FAM83D), RHAMM (FAM83D), CD10 (FAM83F), Human Src Family Kinase-Binding Protein 1 (FAM83G), SMAD2 and SMAD3 (FAM83G), FBXW11 (FAM83H), SKP2 (FAM83H) [90].