EPCAM and hepatitis B virus infection: Mature liver cells do not express EpCAM under normal conditions, however, Breuhahn et al. reported that 75.9% of chronic alcoholic hepatitis, 63.6% of hepatitis C, and 55.6% of chronic autoimmune hepatitis and hepatitis B patients had liver cells expressing EpCAM, suggesting that EpCAM is related to liver cell regeneration [9].