These observations were confirmed in vivo by analysis of normal mouse pancreas and primary pancreatic tumors derived from MUC1 expressing and MUC1-null KPC mice, which showed undetectable levels of c-Jun in normal pancreas as compared to tumor samples, and by the finding that c-Jun expression was further enhanced in tumors expressing MUC1 (Figure 1D). The gene discussed is MUC1; the disease is pancreatic neoplasm.