To independently validate the expression of RHAMM variants in lung adenocarcinoma, we performed real-time quantitative PCR using isoform specific primers for 2 lung adenocarcinoma and paired normal tissues, 4 lung adenocarcinoma cell lines (H1975, HCC827, H3255, and PC9), and a control lung bronchial epithelial cell line (HBEC3-KT). Here, HMMR is linked to lung adenocarcinoma.