The rate of infection (% intracellular viable P. acnes) was 2.8 and 2.2 times higher at 24 h, and 25.3 and 17.6 times higher at 48 h in the Atg5-/- than Atg5+/+ MEF cells at MOI 100 and 1000, respectively. The gene discussed is ATG5; the disease is infection.