In a familial sample from Vietnam including 286 MB and 188 PB leprosy patients (WHO-88), signals located in HLA-DR-DQ, RIPK2, CCDC122, LACC1, and NOD2 were validated (p < 0.05), and the effect was stronger in MB patients for HLA-DR-DQ, CCDC122, and LACC1 [83]. Here, NOD2 is linked to leprosy.