APC and colorectal neoplasm: Comparing these token levels to the β-catenin signaling activities reviewed in [27], the three highest β-catenin stabilizations would correspond to hyperactive signaling by APC mutations in colorectal tumor formation (moderate and high β-catenin token levels), whereas the lowest β-catenin stabilization would correspond to the effects by APC mutations as observed in breast tumor formation (low β-catenin token levels).