FGF2 and diabetic foot: In our previous studies, we developed CGSs impregnated with bFGF mainly to accelerate the healing of chronic ulcers (such as diabetic foot ulcers and venous leg ulcers); however, the present results indicate that, in addition to conventional CSs, CGSs impregnated with bFGF can be used to promote dermis-like tissue formation in the treatment skin defects.