However, in the GWAS study, it was reported that rs13405728 (LHCGR), rs3802457 (C9orf3), rs1894116 (YAP1), rs2272046 (HMGA2), rs4784165 (TOX3), rs2059807 (INSR), and rs6022786 (SUMO1P1) were associated with PCOS risk in Han China (7). The gene discussed is INSR; the disease is polycystic ovary syndrome.