We are extremely grateful to Masayuki Yamamoto (Tohoku University) for providing the Keap1flox/flox and Nrf2−/− C57BL/6 mice that were originally used to generate the Keap1flox/flox and Nrf2−/− SKH-1 hairless mice, John D. Hayes (University of Dundee) for the Keap1 antibody, and to Cancer Research UK (C20953/A10270 and C20953/A18644) for financial support. Here, NFE2L2 is linked to cancer.