CLU and melanoma: There were significant differences between melanoma patients and the healthy controls in the serum levels of the two apolipoproteins related to immune and inflammatory responses (Table 3), with higher levels of SAA (26.8 ± 1.2 μg/ml) and CLU (24.3 ± 0.6 μg/ml) in the serum of melanoma patients than in that of healthy individuals (12.6 ± 1.4 μg/ml and 15.6 ± 0.5 μg/ml, respectively).