The plasma c-Met levels in the tissue c-Met-positive group were 672.57 ± 239.58 ng/ml (95% CI: 318.91 - 1232.67) before EGFR-TKI treatment, 546.15 ± 159.54 ng/ml (95% CI: 360.33 - 971.51) at the time of the best tumor response, and 986.42 ± 578.36 ng/ml (95% CI: 483.36 - 2208.06) with PD. Here, EGFR is linked to neoplasm.