Similar to human prostate cancer tissues, ARF1 expression was also significantly increased in all tested prostate cancer cell lines, including LNCaP, DU145, PC3, 22Rv1, M12 and M2182, as compared to that in the normal prostate P69 and RWPE1 cells (Figure 1C and 1D). The gene discussed is ICA1; the disease is Familial prostate cancer.