INS and diabetes mellitus: Despite this, the extremely wide variation in LH rate reported so far in insulin-treated patients (Hauner et al. 1996; McNally et al. 1988; Partanen and Rissanen 2000; Raile et al. 2001; Kordonouri et al. 2002; Teft 2002; Vardar and Kizilci 2007; Hajheydari et al. 2011; Blanco et al. 2013; Grassi et al. 2014) proves that no systematic educational program has been implemented world-wide to teach people with diabetes how to correctly inject insulin (Blanco et al. 2013; Grassi et al. 2014).