In differentiating between follicular adenoma, follicular carcinoma, and the follicular variant of PTC, several biomarkers have proved to be applicable, including LGALS, hemoglobin, epsilon 1 (HBE1), cytokeratin-19 (CK-19), and thyroid peroxidase (TPO) [62]. The gene discussed is HBE1; the disease is thyroid gland follicular carcinoma.