DCN and breast cancer: Interestingly, SePIA’s integrated analysis reveals putative differences in miRNA co-regulation of TGFBR2 and DCN: 9 of the 10 expressed members appear to target both of the known transcripts of TGFBR2, the ligand-binding receptor for all members of the TGF-beta family, while all 10 miRNAs appear to co-regulate four different transcripts of DCN, an anti-angiogenic factor in breast cancer [47].