EDN1 and diabetes mellitus: However, compared with DM group, the level of IL-6, hs-CRP, TNF-α, ET-1, MDA, and MPO effectively decreased in BPS group (Figures 4(a), 4(b), 4(c), 4(d), 4(f), and 4(h) and Table 5), suggesting that BPS exerts anti-inflammatory effects.