Positive CD31 of immunohistochemical staining showed dark brown, and expressing the endothelial marker protein CD31 was much reduced in glomerular endothelium in rats of BPS group compared to those of T2DM group (Figures 5(a), 5(b), 5(c), and 5(d) and Table 6). This evidence concerns the gene PECAM1 and type 2 diabetes mellitus.