BCR sequencing concurred closely with qPCR transcript levels (red/green versus blue lines, Figure 1a), demonstrating strong correlations between the percentage of clonotypic B-ALL BCRs and qPCR T/C ratios (R2 values>0.87, Supplementary Table S3), while B-ALL clonotypic BCR sequences were detected in all qPCR-positive samples. The gene discussed is BCR; the disease is acute lymphoblastic leukemia.