Taking Crohn’s disease and its drug, infliximab, as an example, Crohn’s disease proved to be negatively connected with T-cell source of chronic lymphocytic leukemia (correlation coefficient −0.15, at top 5 %) and Melanoma (correlation coefficient −0.05, at top 50 %) in our work [30]; infliximab, an antibody against TNF-α, is used for treatment of inflammatory bowel disease (IBD) such as Crohn’s disease [40]. Here, TNF is linked to Crohn disease.