In the present study, no association between ALT levels and AST/ALT ratio with IFG were found, however, Fracanzani et al. [24] previously reported a significant association between diabetes with severe liver disease in adult patients with NAFLD with elevated ALT, but also HOMA-IR in patients with normal ALT, in spite that Manco et al. [25] stated that prevalence of MetS is similar between patients with normal and abnormal ALT values, and that normal ALT values cannot exclude evidence of liver steatosis. The gene discussed is GPT; the disease is metabolic syndrome.