Similar to 4T1-derived cancer lesions, CD11b+F4/80+ cells were also the most abundant infiltrating cell population within both dural and parenchymal brain metastases derived from the PyMT and MDA-MB-231 cancer cell lines (Supplementary Figure S3B), demonstrating that predominant infiltration of microglia/macrophages is cancer cell line-independent. This evidence concerns the gene ITGAM and cancer.