Notably, B16-OVA tumor cells that were incubated either with CD4+ (Figure 6A) or CD8+ T cells (Figure 6B), previously primed with desialylated OVA-pulsed sDCs, showed significantly less viability than those incubated with T cells primed with fully sialylated OVA-pulsed sDCs (Figure 6). Here, CD4 is linked to neoplasm.