Additionally, TCGA melanoma data was analyzed for an inverse correlation between expression of miR-7 isoforms and putative target gene expression, and revealed a negative association between the miR-7-1 isoform and RelA with R = −0.12, p = 0.013, but no significant negative correlations with the other genes that were also associated with survival (Figure 4D and Supplementary Table S6). This evidence concerns the gene RELA and melanoma.