IL2 and neoplasm: Multhoff et al. (2015), have demonstrated that an incubation of NK cells with the Hsp70 protein or an Hsp70-derived peptide (TKD) with the addition of low doses of interleukin-2 (IL-2) for several days (Multhoff et al., 1998), can stimulate the proliferative and migration of NK cells against membrane- hsp70 positive tumor cells (Multhoff et al., 1998; Wattenberg et al., 2014).