A pathological poly-glutamine expansion in ATXN-1, causally related to spinocerebellar ataxia type 1 (SCA1), e.g., was found to induce binding of the protein to RBM17 rather than CiC, thereby promoting disease (Lim et al., 2008). Here, ATXN1 is linked to spinocerebellar ataxia type 1.