APP and Alzheimer disease: Most important, an Aβ42-os propagation within the brains of Tg APP-model mice or WT rats or marmoset (Callithrix jacchus) monkeys also obtained via injections of AD brain extracts or punctures made with steel wires coated with the same extracts (Maclean et al., 2000; Meyer-Luehmann et al., 2006; Eisele et al., 2009; Langer et al., 2011; Hamaguchi et al., 2012; Rosen et al., 2012).