with previous studies on liver and renal fibrosis (Zeisberg et al., 2003; Kinoshita et al., 2007; Yang et al., 2012), suggesting that BMP-7 is one of the possible mechanisms in reversing liver fibrosis by counteracting TGF-β and EMT (Zeisberg et al., 2003). The gene discussed is TGFB1; the disease is renal fibrosis.