RHO and age-related macular degeneration: Rhodopsin delocalization has been observed in other models of retinal degeneration, but rod photoreceptor debris does not build up in the sub-retinal space of AMD patients as it does in RP disorders that involve RPE processing (Jones et al., 2003, 2011, 2012; Marc and Jones, 2003; Jones and Marc, 2005).