Thus, our study intends to evaluate the mRNA expression level of A2bAR, KLF4/KLF15, and key inflammation signaling pathway genes in visceral adipose tissue from Uygur population to investigate the correlation of A2bAR and KLF4/KLF15 with obesity-dyslipidemia induced inflammation in Uygur population. The gene discussed is KLF4; the disease is obesity due to melanocortin 4 receptor deficiency.