ACVR2A and ovarian cancer: The other highly expressed miRNAs were considered to be related to ovarian cancer, GC apoptosis, diminished ovarian reserve, and the release of hormones (details in Table 2), such as miR-143, which was suggested as inhibiting primordial follicle formation by targeting CDK 4 and CDK 6 and cyclins B1 D2, and E2 in pregranulosa cells (36), and miR-181a-5p, which targets activin receptor IIA (acvr2a) and can result in proliferating cell nuclear antigen expression, leading to inhibition of cellular proliferation (37).