The presence of H. pylori infection in gastric cancer was not related to sex or age, but correlated with the depth of tumor invasion, lymph node metastasis, and tumor–node–metastasis stage(P < 0.05 Table 1) and correlated with the COX-2 expression and beta-catenin expression(P < 0.01 Table 1). Here, CTNNB1 is linked to gastric cancer.