Notably, all five CRC cell lines (CACO2, SW480, SW620, HCT-116 and HT-29) expressed lower levels of CASC2 than the non-tumorigenic cell lines (CCC-HIE-2 and HER293), especially CACO2 and HT-29 (Fig. 1C). This evidence concerns the gene CASC2 and colorectal carcinoma.