To evaluate the effect of BARD1β on HR function, RAD51 foci formation was compared among the PARPi-resistant SW480 colon cancer cell lines: SW480 expressing BARD1β, FL BARD1, or both BARD1β and FL BARD1 with and without PARPi treatment (Fig. 3c). Here, RAD51 is linked to colonic neoplasm.